Live News Categories
ORGAN-ON-CHIP
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Microphysiological organ-on-a-chip system for anti-doping research: long-term CYP activity characterization and S107 metabolism in a HepaRG™-based 3D liver model
Engineered Chitosan Nanoparticle Platform Enables Controlled Ibuprofen Delivery and Coordinated Neuroimmune Regulation in a Human Microphysiological Model
Ascending infection of Gardnerella spp. and compartmentalized inflammatory response in fetal-maternal interface organ-on-chip model
Decoding microplastic toxicity on human health: navigating translational challenges using organ-on-chip models
EnView: a tunable microphysiological platform with human crypt-scale topography and independent apical-basal flow for long-term culture and imaging of colonic epithelial monolayers
Integrated "gut-liver"-on-a-chip (iGLoC): an immune-competent and metabolically active microphysiological model of the gut-liver axis for drug screening, validated by abemaciclib pharmacokinetics, hepatotoxicity, and drug-drug interaction studies
Zonation Hallmarks in Human PSC-Derived Hepatic Organoids Integrated into an Immune-Compatible Organ-on-Chip for Liver Injury Modeling
Electrochemical impedance spectroscopy supporting live imaging for barrier assessment in a microphysiological system
Chamber-Design-Associated In Situ Formation of HepG2 Spheroids in a Perfusable Organ-on-a-Chip
Systematic evaluation of deep learning design choices for image-based organ-on-chip quality assessment
Microphysiological models of human gastrointestinal diseases
Engineering human multi-organ tissue chip niches for drug absorption, distribution, metabolism, excretion and toxicity prediction
Advances in engineering organ-on-a-chip models of angiogenesis
Real-time integrated and multiplexed electrochemical sensor for reactive oxygen species in a high-throughput microphysiological system
Sensor-Integrated Organ-on-a-Chip Platforms: Advances in Drug Evaluation and Disease Modeling
Microphysiological Systems Integrating Bioprinting, Organoids, Organ-on-a-Chip, and AI: Next Generation Platforms for Pharmaceutical Development
Artificial intelligence across Organ-on-a-Chip workflows: current implementations and future approaches
Tumor-on-chip and cancer microphysiological platforms: knowledge structure, thematic evolution, and the emergence of organoid-integrated models, 2010-2025
Bridging the gap: using organ-on-a-chip technology to evaluate nanoparticle enzyme replacement therapy for lysosomal storage diseases
Hydrogels and microfluidics: toward more physiologically relevant organ-on-a-chip models
ORGANOIDS
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Human brain organoids reveal MGE interneuron defects independent of mTOR-hyperactivation in genetic focal epilepsy
Constructing functional neural circuits to model amyotrophic lateral sclerosis with induced pluripotent stem cell-derived brain organoids
Neural Organoids and Organoid Extracellular Vesicles for Spinal Cord Injury Repair
Characterization of human induced pluripotent stem cell (hiPSC)- derived Kidney Organoids as a Platform to Assess Drug-Induced Nephrotoxicity
Long-Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair
Programmable apoptosis circuits enable subtractive engineering of stem cell-derived organoids and embryoids
Modeling ocular tissues with organoids: A review of techniques and applications in lacrimal gland, cornea, lens, and retina organoid
Translational applications and clinical utility of organoids in ovarian cancer: a systematic review
Generation of Spontaneously Beating Neuromyocardial Organoids with Neural Crest-Derived Proprioceptive-Biased Neurons and Real-Time Respirometry
Editorial Expression of Concern: Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
Automated Spheroid and Organoid Image Analysis from Rule-Based Methods to Deep Learning
Lung Cancer Organoid Models for Studying Resistance to Anti-Angiogenic Therapy: Mechanisms and Applications
Improved quality and reproducibility of cerebral cortical organoids under microfluidic culture conditions: a proof-of-concept study
Multi-omics and spatial analysis of microgravity-grown glioblastoma organoids reveal superior modeling of advanced disease after long-term spaceflight
Self-assembled Carbon Nanotube/Extracellular Matrix Hydrogel as a Promising Matrix for Organoid Growth and Functional Maturation
Modelling herpes simplex virus type 2 and Zika virus replication in mouse vaginal organoids and human vaginal spheroids
Tooth organoids: bridging developmental biology and regenerative dentistry
CX3CL1 (fractalkine)-CX3CR1 interface drives CD8⁺ T cell-induced neurodegeneration in human brain organoids
Human iPSC-derived liver organoid model multicellular tissue responses and therapeutic rescue in Wolman disease
Human iPSC-derived lens organoids recapitulate lens development and morphogenesis in vitro
DIGITAL TWINS
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Digital Twin Control Framework Uncovers Individualized Cross-Scale Links Between Functional Connectivity Deviations, Communication Impairment, and Molecular Mechanisms in Autism
The Role of Digital Twins in Clinical Trials: A New Perspective on Methodological and Statistical Challenges
Sex-based differences in bi-atrial voltage in atrial fibrillation: a multimodal and digital twin approach to distinguish physiological variation from pathological remodelling
Single-cell-level digital twins for preterm birth prevention strategies
Effects of a Generative AI Virtual Patient on Serious Illness Communication Skills: Randomized Controlled Trial
Nonlinear stability phenotypes and collapse dynamics of multi-organ radiomics in total-body PET imaging: toward digital twin-oriented robustness assessment
Q-LCAN: Anatomy-Constrained Quantum-Agentic Systems for MRI-Derived Structural Surgical Digital Twins in Uterine Adenomyosis
Digital twins in hospital operations management: a structured review and quantitative content analysis of decision support, workflow engineering and resource allocation
A Biomanufacturing Digital Twin for Consistent N-1 Seed Bioreactor Transfers for Commercial Monoclonal Antibody Production
From static digital articulation to the dynamic (4D) digital virtual patient: An umbrella review of digital occlusal analysis and jaw-motion tracking
Exploratory bone-brain transcriptomic associations and an ODE-based digital-twin framework for fracture healing
Exploring nursing students' communication experiences with artificial intelligence-supported virtual patients: a qualitative study
Digital twins in toxicology: Toward predictive, personalized and real-time risk assessment
Digital twin validation and predictive value of delta radiomics based on tabular transformer for synergistic muscle imbalance in lumbar disc degeneration
Agent-based simulation and digital twins in heart failure care: Current evidence, validation and implementation barriers
Graph neural network for predicting reentrant drivers in atrial digital twins
Data, Process, and Data-Driven Representations of Digital Twins in Diabetes: Scoping Review
Retrieval-Augmented Simulation for Interpreting Probabilistic Digital Twins in Type 1 Diabetes
Quantum-Inspired Graph Neural Digital Twins for the sub-microsecond topological co-design and temporal degradation modeling of cellulose, hemicellulose, and lignin smart gels
Self-adaptive nanophotonic metasurfaces enabling digital twins: toward continuous personalized healthcare in aging and disability
AI & MACHINE LEARNING
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Deep learning multimodal fusion model based on ultrasound images and clinical-ultrasound texts for differentiating benign and malignant renal tumors
Clinical integration of artificial intelligence for diagnosis, risk prediction and management of rare cardiovascular diseases
A five-gene mitochondrial-lipid metabolism signature for Alzheimer's disease diagnosis identified by machine learning and validated in independent cohorts
Artificial intelligence in hepatitis: Advances in diagnosis, treatment optimization, and prognostic prediction
Applications of Artificial Intelligence in Parasitology: A holistic perspective from diagnosis to therapeutics
Predicting Progressive Pulmonary Fibrosis in Idiopathic Inflammatory Myopathy-associated Interstitial Lung Disease: A Machine Learning Approach Integrating Quantitative CT and Clinical Features
Exploratory structure-function associations in retinal vein occlusion-associated macular edema using deep learning-based quantification of OCT biomarkers and microperimetry
Revealing protein structural transitions in the era of generative artificial intelligence
From chatbot to clinical copilot: the role of generative artificial intelligence in nuclear medicine reporting and data extraction
Artificial Intelligence-Driven Molecular Imprinting for Efficient Polymer Design and Enhanced Liquid-Phase Separation
[Artificial intelligence in the early detection of psychotic disorders: opportunities and limitations of clinical implementation]
Development and Evaluation of a Two-Stage Machine Learning Multivariable Model to Support Clinical Decision-Making in Thrombophilia Management
Deep learning-based detection of pneumoperitoneum on computed tomography: performance and clinical feasibility
Machine learning-assisted surface-enhanced Raman spectroscopy technique in dried human blood serum analysis for rapid diagnosis of papillary thyroid carcinoma and central lymph node metastasis
Machine Learning Model Using Clinical and Contrast-Enhanced MRI Features Differentiates Cerebral Tuberculoma from Lung Cancer Brain Metastasis
Machine Learning Models for Early and Accurate Prediction of Disseminated Intravascular Coagulation: The Diagnosis of DIC Depends on the Diagnostic Tool
Machine Learning with Muscle Ultrasound for Osteoporosis Classification: Reporting Discrepancies, Validation, and Clinical Role
Validation of a Computational Histology Artificial Intelligence-based Biomarker for BCG Treatment in Non-muscle-invasive Bladder Cancer in the ANZUP 1301 Randomized Phase 3 Trial
13 AI drug discovery companies you should know about
‘We’ve been taking our time’: Buzzy AI biotech Xaira reveals antibody platform, first taste of pipeline
CLINICAL TRIALS
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Effects of inspiratory muscle training on posture and respiratory muscle performance in forward head posture: Randomized controlled trial
ENZARAD (ANZUP 1303): Phase 3 Trial of Enzalutamide With Androgen Deprivation Therapy and Radiation Therapy in High-Risk Localized or Locally Advanced Prostate Cancer
Phase II Study of Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous Cell Carcinoma: Final Analysis
COMPANION-002: A Randomized Phase 2/3 Trial of Tovecimig Plus Paclitaxel versus Paclitaxel Alone as a Second-line Therapy in Patients with Advanced Biliary Tract Cancer
STAT+: Novartis multiple sclerosis treatment cuts rates of relapse in pivotal trials
Prilenia and Ferrer secure EU authorisation for Phase III HD trial
Safety and efficacy of lacnotuzumab, a colony-stimulating factor 1 antibody for the treatment of tenosynovial giant cell tumors: a randomized phase II trial
Cefepime-Zidebactam for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria, Including Metallo-β-Lactamase Producers: A Phase 2, Open-Label, Single-Arm, Multicenter Study
Effect of a polynutraceutical juice (Indian gooseberry, ginger and curry leaves) as an adjunct to oral antidiabetic drugs on fasting blood glucose in type 2 diabetes: A randomized controlled trial
A randomised controlled trial comparing a 100% chitosan haemostatic dressing and a manual compression device following transradial coronary intervention
Socioeconomic position and the effect of price interventions on healthier and less healthy food on food selection in a simulated food delivery app: a randomised controlled trial - CORRIGENDUM
Topical Ciprofloxacin for Non-Perforated Acute Otitis Media: A Randomized Controlled Trial
Effect of a Researcher-Supervised Walking Program With Smartphone-Based Step Monitoring on Sleep Quality in Older Psychiatric Inpatients: A Randomized Controlled Trial
A phase III trial of ALZT-OP1 (cromolyn + ibuprofen) in early Alzheimer's disease: Primary results and exploratory analyses by APOE4 genotype
Ibrutinib and standard immunochemotherapy in younger, high-risk patients with diffuse large B-cell lymphoma: A phase II study of GLA
Bimekizumab in Chinese Patients with Active Non-Radiographic Axial Spondyloarthritis: 52-Week Results from the Phase 3 BE MOBILE 1 Study
Lynch’s rhPDGF-BB IND secures FDA clearance for Phase II trial
People are taking an unapproved weight-loss drug. AI found something surprising
Author Correction: FcRH5×CD3 bispecific antibody cevostamab in relapsed or refractory multiple myeloma: a phase 1 trial
Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial
REGULATORY
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International Regulatory Status and Reimbursement Recommendations of Haematological Malignancy Drugs Withdrawn from the FDA Accelerated Approval Pathway
An update on post-marketing safety signals of sugammadex: A retrospective pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS)
Taxanes versus platinum derivatives for ovarian cancer: a comparative disproportionality analysis using the FDA adverse event reporting system database
Timing of FDA-Defined Adequate BCG Therapy and Oncologic Outcomes in High-Risk Non-Muscle-Invasive Bladder Cancer
Lynch’s rhPDGF-BB IND secures FDA clearance for Phase II trial
ASO Visual Abstract: Real-World Adoption of Adjuvant Immune Checkpoint Inhibition in Stage IIB/IIC Melanoma Following FDA Approval
FDA approves subcutaneous starting dose for Alzheimer drug
FDA Advisory Committee Recommends Previously Banned Peptides for Compounding
Bridging drug labels and precision medicine: pharmacogenomic opportunities in recent US-FDA drug approvals
FDA approves hepatitis B antisense drug
A Target Product Profile Framework to Guide Patient-Centered Development, Regulatory Approval, and Market Access of Digital Therapeutics for Substance Use Disorders
GSK Immunotherapy Gets Accelerated FDA Approval for Treating Rectal Cancer
Sirolimus-based immunosuppression and reported rejection or death in heart transplant recipients using the U.S. Food and Drug Administration Adverse Event Reporting System
Food and Drug Administration Grants Ultragenyx's Fayuvi™ First-Ever Approval for Sanfilippo Syndrome Type A Treatment
Real-World Adoption of Adjuvant Immune Checkpoint Inhibition in Stage IIB/IIC Melanoma Following FDA Approval
Comparative Evaluation of Power-Law and Viscoelastic Hemolysis Models in the FDA Nozzle Benchmark Geometry
Malfunction Reporting Patterns in Life-Supporting Versus Noninvasive Ventilators: A Stratified Text-Mining Analysis of the FDA Device MAUDE Database
FDA Approves a Second Weekly Basal Insulin Option for Type 2 Diabetes
FDA Policy Changes on Stability Studies for PET Drugs Manufactured Within Networks
Abbott nabs FDA approval for new CardioMEMS HF System that allows heart readings to be seen at home
DRUG DISCOVERY
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Small-molecule ferroptosis inducers and sensitizers in anticancer drug discovery: medicinal chemistry, structure-activity relationships, and translational perspectives
How Omics Technologies Are Transforming Biological Research and Drug Discovery
Anticancer drug discovery: Embracing the next wave of innovation
Structural characterization and structure-activity relationship of polysaccharides from Curcuma kwangsiensis extracted sequentially: Anti-Alzheimer's activity in an AlCl3-induced zebrafish model
Methadone: Historical success, modern challenges and lessons for opioid drug discovery
Synthesis, bioevaluation and structure-activity relationship of podocarpamide derivatives from Zanthoxylum alkaloids (ZAs)
PARP-1 selective inhibitors: A new direction in drug discovery to improve the therapeutic index of PARP-targeted cancer therapy
Structure-activity relationships and mechanisms of natural polysaccharides in modulating kidney diseases via the microbiota-gut-kidney axis: A review
α‑Aminophosphonates in anticancer drug discovery: synthetic strategies, anticancer activities, structure-activity relationships and molecular mechanisms
Ultrasound-assisted deep eutectic solvent extraction of polyphenols from Sophora alopecuroides L. seeds: process optimization, antioxidant evaluation and machine learning-assisted structure-activity interpretation
A new era of GPCR drug discovery: From receptor deorphanization to precision therapeutics
Cell Painting method reveals drug differences in 3D cancer cells
Human Induced Pluripotent Stem Cells in Rare Neurological Disorders: Opportunities and Challenges for Disease Modeling and Drug Discovery
Integrative Metabolomics and Molecular Docking as a Drug Discovery Approach: A Case Study of Microbial Cyclo(Gly-L-Pro) Targeting Alzheimer's Disease
4-Diketopyrrole-2-carboxamide derivatives affecting HBV capsid assembly: structure-activity relationship around the GLP-26 scaffold
Natural products for benign prostatic hyperplasia (BPH): structure-activity relationships and pathway mechanisms
13 AI drug discovery companies you should know about
Concept Life Sciences appoints Dr Adrijana Vinter as Chief Executive Officer
Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity
Evaluating generative models for structure-based drug discovery from de novo design to lead optimization
INDUSTRY
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US targets Chinese biotech investment, but licensing deals remain exempt
STAT+: Treasury proposes major restrictions to U.S. investment in Chinese biotech sector
Egypt reforms obsolete pharmaceutical pricing framework
Beyond dilation: six biotechs advancing pulmonary hypertension therapies
GLP-1 muscle loss: the next battleground in obesity treatment (Part 2 of 3)
Oncology biotech news: key moves to watch in October 2026
Preclinical Pulse: The research catching our eye in October 2026
Pushing biotech forward in France: 10 companies to know about
ArriVent’s phase 3 lung cancer trial flops, sinking stock
Forbion’s ‘landmark’ €2.3B fundraise to benefit 30 ‘high potential’ biotechs
AstraZeneca hopes to ‘achieve amazing things’ with new Kendall Square R&D center
TRex Bio stomps toward $111M IPO, as Retension and Lycia also gear up to go public
Biotech’s peptide shows promise as ‘bait molecule’ to treat neuropathic pain in mice
Vaxcyte’s stock jumps as pneumococcal vaccine holds its own against Pfizer's, Merck’s shots
Gate CEO sees expanded $870M pact with Lilly as ‘vote of confidence’ in biotech’s platform
‘We’ve been taking our time’: Buzzy AI biotech Xaira reveals antibody platform, first taste of pipeline
Immunotherapy startup Adecto blames ‘risk-averse funding environment’ for closing down
There Is No Such Thing as a Typical Biotech
Otsuka JV recalls one lot of sodium chloride over labeling issue
'Europe does not value what you do': 9 pharmas make urgent call for bloc to beef up innovation muscle
RESEARCH
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Scientists discover how pancreatic cancer rewrites its DNA to escape treatment
Your blood could reveal inflammatory bowel disease 10 years before diagnosis
Glioblastoma breakthrough reveals how brain cancer cells become more aggressive
Scientists discover a hidden messaging system deep inside the brain
Scientists discover a hidden immune weapon against deadly lung cancer
Scientists discover a surprising secret behind the human brain’s wrinkles
Too much RNA can starve cells of energy, scientists discover
Scientists discover immune pathway behind radiation-induced lung damage
Scientists finally uncover why statins can cause muscle pain
Scientists discover a surprising link between vitamin C and cancer survival
Why painful arthritis can return stronger after cancer treatment
Just 3,000 steps a day may help slow Alzheimer's, scientists find
Magic mushroom ingredient takes the fight out of aggressive fish
Scientists discover that male and female skin play by different rules
Scientists discover how deep sleep builds muscle, burns fat, and boosts the brain
Scientists discover how exercise reverses muscle aging
Scientists discover a surprising danger in smaller cancer cells
Scientists find a surprising genetic twist behind octopus intelligence
Scientists find hidden driver of aging and a simple amino acid that fights memory loss in mice
Scientists discover 5 hidden brain patterns behind depression
TECHNOLOGY
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A DNA Logic-Gated Cascade Amplification Biosensor for Highly Specific Electrochemical Detection of Circulating Tumor Cells
Pregnancy Outcomes of Intrauterine Insemination Using Microfluidics ZyMot Device for Patients With High Sperm DNA Fragmentation: An Exploratory Retrospective Study
An OR-logic-gated polarity-switching biosensor for multiplexed dual-mode thalassemia screening
A chitosan leaky waveguide biosensor for measurement of DNA biomarkers
Chemiluminescence and electrochemiluminescence biosensors for cancer biomarker detection: analytical advances, liquid-biopsy applications, and translational challenges
Marangoni Effect-Mediated Interfacial Regulation of Oriented Laser-Induced Graphene-MOF Heterojunctions toward High-Performance Dual-Mode PEC-SERS Biosensor
Engineering a 3D microfluidic platform to model neuroimmune interactions in periodontal inflammation
Benchmarking segmentation methods for spatial transcriptomics
Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia
Acoustofluidic enrichment of small extracellular vesicles: physical principles, microfluidic implementations, and prospects for Parkinson's disease liquid biopsy
Monkeypox on a disc: Portable centrifugal microfluidic platform for multi-assay colorimetric LAMP
A Graphene Oxide-Functionalized Fiber Optic Biosensor for Breast Cancer Biomarker Detection: Toward Developing a Highly Sensitive Multi-Fluid Diagnostic Platform
Integrated Droplet Microfluidic Platform for Single-Spheroid Photothermal Nanotherapy and Morphology-Driven Response Prediction
MXene-polydopamine-cyanobacteria photobioelectrochemical biosensor for atrazine detection in environmental waters
An Integrated Cascade-Amplified Microfluidic Biosensor for Reconfigurable Profiling of CRC-Associated Faecal Extracellular Vesicle Surface Proteins
One-pot dual RPA-CRISPR/Cas12a lateral flow biosensor for rapid detection of carbapenemase-producing Klebsiella pneumoniae
Three-dimensional microfluidic nanoprecipitation of zein-loaded polyethylene glycol poly(lactic-co-glycolic acid) nanoparticles with sustained-release antibacterial activity
Transistor Biosensors: A Path to Accessible, Minimally Invasive Early Screening for Alzheimer's Disease
Nonlinear Flow Generation in Microfluidic Impedance Pumps
Machine-learning-integrated NLRC3 and cardiac troponin T dual-analyte lateral-flow biosensor for point-of-care acute coronary syndrome screening and acute myocardial infarction-unstable angina discrimination
CRISPR & GENE EDITING
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Spatially Resolved Multiplex Detection of Cytokines in Parkinson's Disease Rat Brain via CRISPR/Cas Biosensing
Establishment and preliminary application of the Mo RPA-CRISPR/Cas12a rapid detection method
Base editing-mediated exon-specific knockout of glutamine synthetase generates a high-productivity CHO cell line for antibody manufacturing
A phospholipase B effector exploits membrane lipid divergence to drive inter-Bacteroides competition and enables universal genome editing
On-Site, Highly Sensitive, and Multisignal Detection of Cucumber Bacteria via CRISPR/Cas12a Coupled with Duplex Recombinase Polymerase Amplification
Scaffold RNA Reengineering for a Leakage-Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics
A first for CRISPR: powerful prime editing alters DNA directly in the human body
One-pot dual RPA-CRISPR/Cas12a lateral flow biosensor for rapid detection of carbapenemase-producing Klebsiella pneumoniae
Transcriptomics of independent CRISPR-edited cell lines reveal ciliary-specific ARL13B dependent changes
An aptamer-regulated CRISPR/Cas12a system based on split crRNA for theophylline and tobramycin detection
Pooled CRISPR screens identify genes and non-coding genomic regions that regulate red blood cell density
Great gene editing. Now prove it without overcomplicating the analysis
Structural basis for loop-dependent inhibition by AcrIIC1 anti-CRISPR proteins
Author Correction: UNCOVERseq enables sensitive and controlled gene editing off-target nomination across CRISPR-Cas modalities and systems
A cryptic binding pocket regulates the metal-dependent activity of Cas9
Manipulating rRNA levels with CRISPR
Correction: CRISPR/Cas9-mediated gene correction of Wilson disease H1069Q point mutation in patient-specific induced pluripotent stem cells
Site-specific RNA photocrosslinking of CRISPR-associated and viral RNA-binding proteins using genetic code expansion
Bigger than CRISPR? A guide to the latest genome editors
CRISPR-based gene drive systems alter the transcriptome in Anopheles gambiae mosquitoes
CELL & GENE THERAPY
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Nearly one third of patients with advanced melanoma saw tumors disappear completely after receiving TIL therapy plus pembrolizumab immunotherapy
CAR T cells targeting fibroblast activation protein-α for the treatment of pulmonary fibrosis
STAT+: Patient dies in Bristol Myers Squibb autoimmune CAR-T trial
Determinants of response to CAR T cell therapy in a multicenter, multi-trial cohort analysis of patients with lymphoma
Determinants of response to CAR T cell therapy in a multicenter, multi-trial cohort analysis of patients with lymphoma
Local T-cell engager secretion reprograms endogenous antitumor immunity and enhances CAR-T cell persistence in solid tumors
Engineered hydrogels for boosting chimeric antigen receptor (CAR)-cell therapy: strategies and biomedical applications
CD8 T-cell exhaustion linked with CAR T-cell failure can be mitigated by a non-alpha IL2 receptor agonist
T Cell Receptor-Engineered T Cell Therapy in Solid Tumors: Where We Stand and What's to Come
Alcon Expands Its Cell Therapy Ambitions With $550M Neurotech Pharma Acquisition
Translation of in vivo CAR-T in China
Innovations and emerging trends in adoptive cell therapies for solid tumors: engineering strategies and clinical translation
Clonal circulating tumor cell mobilization following chimeric antigen receptor T-cell therapy in metastatic castration-resistant prostate cancer
Second Primary Malignancy in Patients with DLBCL Receiving CAR T Therapy and Other Systemic Anticancer Therapy: Real-World Evidence from a Large US National Claims Database
Next-Generation CAR-T Cell Therapy: From Modular Design to Clinical Expansion
ROR2-expressing acute myelogenous leukemia cells can be selectively targeted by anti-ROR2 CAR T cells
Scientists reprogram immune cells inside the body to fight cancer
Novartis pens $7.8B deal for Abogen's in vivo autoimmune T-cell engager
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases
Author Correction: Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
BIOPRINTING
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Nondestructive quality control across the life cycle of bioprinted products
Enhancing the Structural Integrity of 3D Bioprinted Urethral Grafts for Clinical Applications using GelMA-Fibrinogen Bioinks Infused with Human Primary Cells
Accelerated Formulation Screening of Multi-Component Bioinks via a Deep Learning-Integrated High-Throughput Gradient Printing Platform
Fungal-Derived Chitosan-Based Bioinks Enable Multifunctional Musculoskeletal Tissue Engineering via Enhanced Bioactivity
Granular hydrogel bioink for macroporous pancreatic spheroid scaffolds
Biofabrication of osteochondral composite scaffolds: advances in multi-material bioprinting, functional microenvironment engineering and orthopedic translation
A multi-component polymeric bioink formulation developed using an in-house integrated bioextruder
3D-bioprinted dual-factor nerve conduits promote neurovascular co-regeneration via activation of the PI3K/AKT and MAPK/ERK pathways
Enzymatic cross-linking collagen-based bioink for 3D bioprinting of endometrial model with endometrial epithelial organoids
Emerging Strategies for Bioprinting Organized Musculoskeletal Tissues with Biomimetic Collagen Architecture
Airflow controlled droplet bioprinting enables high-throughput generation of iPSC-derived thymic organoids within vivoT cell functionality
Next-generation hydrogels and strategies to recreate 3D tumour microenvironments for osteosarcoma: from bioprinting to therapeutic testing
Protocol for fabricating immune-regulatory bone organoids via plant-based bioinks
3D bioprinting and scaffold technology applications for the management of lung diseases
3D bioprinted porous PLLA implants with dual gene modified BMSCs for osteoarthritis cartilage repair
Cell-Laden 3D-Bioprinted Artificial Skin Grafts for Tissue Engineering Wound Healing
MLATE V3: An Open-Source Multi-Tissue AI Framework for Data-Driven Optimization of 3D-Printed and Bioprinted Scaffolds
3D bioprinting in dermatological therapeutics: Technologies, applications, and clinical perspectives
PRECISION MEDICINE
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Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia
Whole-genome and transcriptome analysis in relapsed/refractory non-Hodgkin lymphoma: Results from a multicentre precision oncology cohort
Role of Plasma Proteins in the Association Between Socioeconomic Status and Cardiovascular Disease Events: Results From Trans-Omics for Precision Medicine Cohorts
Current and Emerging Therapies for Generalized Myasthenia Gravis: Toward Precision Medicine
Precision medicine for pediatric cardiomyopathy: lessons from pediatric oncology
Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia
Biologics in alopecia areata: promise, paradox, and the precision medicine frontier
Networked innovation in the new modality era: strategic insights from spin-offs and precision medicine
Readiness for precision medicine: pharmacogenomic literacy among adults surveyed in the United Arab Emirates: a cross-sectional study
Advances in Single-Cell and Spatial Omics for Glioblastoma Precision Medicine
The right patient, the right moment, the right therapy: reimagining precision oncology from the bedside
Evaluation of a pharmacist-led pharmacogenomic service and provider acceptance at VA Puget Sound
Bridging drug labels and precision medicine: pharmacogenomic opportunities in recent US-FDA drug approvals
Response Letter: ACE Inhibition in PH-COPD: Severity Stratification Unlocks a Precision Medicine Opportunity
Precision oncology in advanced melanoma: molecular landscapes and personalized therapy recommendations from the Molecular Tumor Board Freiburg
Advancing functional treatment prediction for precision oncology
Biologicals at the Allergy-Cancer Interface: Advancing AllergoOncology Through Bidirectional Precision Medicine-An EAACI Editorial
The ESMO Scale for Clinical Actionability of Molecular Targets, version 2 (ESCAT v2): an evidence-based framework for ranking alterations as actionability and resistance biomarkers in precision oncology
Feasibility of a personalised medicine clinic for children with asthma: the PRISTINE 2 study
An imprecise label in the era of precision medicine: labelling and access for daraxonrasib, the first pan-RAS inhibitor approval
STEM CELLS
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Constructing functional neural circuits to model amyotrophic lateral sclerosis with induced pluripotent stem cell-derived brain organoids
Characterization of human induced pluripotent stem cell (hiPSC)- derived Kidney Organoids as a Platform to Assess Drug-Induced Nephrotoxicity
Are 5G radiofrequency electromagnetic fields and PARP1 interfering in the development of human iPSC-derived dopaminergic neurons?
Electrophysiological remodeling in the hypertrophic cardiomyopathy MYBPC3 R943X mutant in human iPSC-derived cardiomyocytes and modulation by IKto-targeting drugs
Human Induced Pluripotent Stem Cells in Rare Neurological Disorders: Opportunities and Challenges for Disease Modeling and Drug Discovery
Exploring the therapeutic potential of human iPSC-NPC-based therapy in MPS IIIA
A novel strategy to generate human iPSCs with enhanced mesodermal and endodermal differentiation capacity
HER2 CAR-expressing iPSC-derived iNKT cells exhibit multifaceted immunomodulatory functions beyond direct tumor killing
Spheroid-based generation of 3D myogenic tissues using transgene- and sorting-free differentiation of hiPSCs
Genetically Defined Acute Myeloid Leukemia Induced Pluripotent Stem Cell Clones Reveal Selective Impairment of Hematopoietic Development
Chemical reprogramming of human pluripotent stem cells into 8-cell-like states
Beyond marker expression: An ESC-informed framework for engineering and validating chicken induced pluripotent stem cells
The prognostic impact of CEBPA mutation in acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation
Ketamine induces synaptic and monoaminergic remodeling in human iPSC-derived neurons
Human iPSC-derived liver organoid model multicellular tissue responses and therapeutic rescue in Wolman disease
Generation of Spinocerebellar Ataxia 27B iPSC Lines and Isogenic Controls
Human iPSC-derived lens organoids recapitulate lens development and morphogenesis in vitro
Inhibition of endogenous TGF-β normalizes extracellular matrix deposition in hiPSC-derived fibroblasts
New signaling pathway enhances blood stem cell transplantation outcomes
Correction: CRISPR/Cas9-mediated gene correction of Wilson disease H1069Q point mutation in patient-specific induced pluripotent stem cells
NEW APPROACH METHODS
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Epigenetic markers as predictors of neurotoxicity and abuse potential of psychotropic drugs: integration of epigenetic modifications in New Approach Methodologies
Integrating New Approach Methodologies (NAMs) into Read-Across Evidence Streams for Short-Chain Nitroparaffins
Evaluating the biological effects of caffeine-related compounds methylliberine and theacrine by integrated in silico and in vitro new approach methods (NAMs)
New approach methodologies in nanomedicine: bridging the gap between in silico, in vitro, and in vivo systems
A novel double-mAb sandwich ELISA utilizing broad-spectrum neutralizing antibodies as an in vitro alternative to the rabies vaccine NIH potency assay
Towards the One Exposome: harnessing artificial intelligence and digital health technologies across One Health toxicology, new approach methodologies, and environmental public health
Animal Models for Interventional Oncology Research: Overview and Considerations in the Era of New Approach Methodologies
An overview of In vitro genotoxicity testing strategies for fragrance materials: Addressing false positives and advancing non-animal approaches
New approach methodologies to model the female reproductive tract: advances and opportunities for nanomedicine
Advancing component-based mixture risk assessment using new approach methodologies: An environmental case study
Pediatric Developmental Safety Assessment and New Approach Methodologies: US FDA/Triangle CERSI Workshop Report
New approach methodologies in pharmaceutical development: Survey insights on adoption, infrastructure, and the path to broader implementation
Quinoa and Peanut Extracts as Alternatives to Animal-Derived Extracellular Matrix Proteins in Cultured Meat Production
Editorial: Shaping the future of predictive toxicology: addressing challenges and new approach methodologies
Engineering 3D neural models of neurodegeneration: the Neural Microenvironment Design Code (NMDC), design principles, and emerging new approach methodologies
New approach methodologies for in vitro detection of chemical-induced cholestatic liver injury
Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling
AI-integrated human-relevant alternatives to animal experimentation in drug development: Toward a predictive translational ecosystem, from in vitro and in silico models to clinical and real-world evidence
New approach methodologies: drug screening platform to identify antifibrotic compounds
FUNDING & VC
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STAT+: AI drug firm Pathos raises $237 million, pushing valuation to $3 billion
Alcon Expands Its Cell Therapy Ambitions With $550M Neurotech Pharma Acquisition
Merck KGaA’s $1.1B Silence Therapeutics Buyout Brings RNA Drug for Rare Blood Cancer
RougeTx launches with $58 million series A financing for HHT therapy
IMMUNOTHERAPY
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Nearly one third of patients with advanced melanoma saw tumors disappear completely after receiving TIL therapy plus pembrolizumab immunotherapy
High prevalence of TROP2 expression identifies EBV-positive gastric cancer as a candidate for TROP2-directed antibody-drug conjugates
IgY-Based Immunotherapy Against MDR/XDR/PDR Bacterial Infections: Mechanisms and Experimental Evidence From In Vitro and In Vivo Studies
Immune checkpoint inhibitor-associated cardiotoxicity: incidence, diagnosis, and management
Use of adjuvant immunotherapy and early overall survival in stage III Merkel cell carcinoma
Celltrion and Kaigene sign $580m licence deal for KG013
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial
Key Challenges on the Path toward Precision Immunotherapy for Large B-cell Lymphoma
Advances in resistance mechanisms and counterstrategies for antibody‑drug conjugates in HER2‑low and HER2‑ultralow breast cancer (Review)
Unstable immune cells linked to severe cancer immunotherapy side effects
Association of pre-existing cardiovascular disease with cardiovascular and clinical outcomes in patients receiving immune checkpoint inhibitors
GSK Immunotherapy Gets Accelerated FDA Approval for Treating Rectal Cancer
Jemperli Could Let Some Rectal Cancer Patients Skip Chemotherapy, Radiation And Surgery
Why painful arthritis can return stronger after cancer treatment
Author Correction: FcRH5×CD3 bispecific antibody cevostamab in relapsed or refractory multiple myeloma: a phase 1 trial
In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles
Bowel cancer “melted away” after immunotherapy, then stayed away
Cancer-fighting t cells burn out. Scientists may have found a fix
Genmab’s latest phase 2 data spur claim ADC is ‘clearly superior’ to AbbVie’s Elahere
Immunotherapy startup Adecto blames ‘risk-averse funding environment’ for closing down
MICROBIOME
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Fecal microbiota transplant in the treatment of inflammatory bowel diseases: new perspectives on delivery, mechanism, and clinical positioning
Gut Microbiota in Alzheimer's Disease and Healthy Aging: Mechanisms, Prevention Strategies and Healthcare Burden
β-defensin 130 Counteracts ETEC-K88 Infection in Mice: Mechanistic Insights from Gut Microbiome and LC-MS-Based Metabolomic Correlation Analysis
Clostridium butyricum: A Promising Probiotic for Inflammatory Bowel Disease through Modulation of Gut Microbiota and Immunity
Bifidobacterium animalis subsp. lactis C-2 Alleviates DSS-induced Ulcerative Colitis via the Microbiota-tryptophan Metabolism-AhR Pathway
Impact of Two High-Fiber Dietary Transitions on Fecal Consistency and Microbiota Composition in Captive Dromedary Camels (Camelus dromedarius) With Chronic Recurrent Diarrhea: A Pilot Study
Microbiota-Derived Extracellular Vesicles in Cancer Prognosis: A Systematic Review and Contextual Evidence Map of EV-Associated Microbial Signals
Baicalin and levofloxacin exert divergent modulation on gut microbiota and metabolome crosstalk in DSS-triggered ulcerative colitis
A Bibliometric and Visualized Analysis of Global Trends in Gut Microbiota and Metabolic Syndrome Research
Amino acid availability influences Staphylococcus aureus interaction with the nasal microbiota in a strain- and community-specific manner
Microbiome interactions in renal cell carcinoma: evidence, challenges and opportunities
The human microbiome and chronic disease: ten strategic priorities for research and public health
Sodium oligomannate remodels gut redox adaptation and promotes microbiota-derived indole-3-propionic acid production to alleviate Alzheimer's disease
Co-housing Alters Gut Microbiota and Disease Severity in Experimental Pemphigoid Disease
Unstable immune cells linked to severe cancer immunotherapy side effects
Disentangling microbiota-dependent and -independent impacts of antibiotics on host physiology
Publisher Correction: Microbiota-derived 10-hydroxystearic acid activates PPARα to restore gut epithelial barrier integrity and enhance anti-retroviral therapy
Discovering gut microbiome signatures that predict adverse and reverse cardiac remodeling in preclinical heart failure
Genome mining of the tumor microbiome reveals biosynthetic diversity and potential pathology-modulating metabolites
Sugar-rich foods exacerbate antibiotic-induced microbiome disruption
CARDIOVASCULAR
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Exposomic Determinants in Heart Failure Among Older Adults - Mechanistic Links, Clinical Evidence, and Future Perspectives
Using Implementation Science to Improve Guidelines-Based Care to Lower Atherosclerosis Risk Due to Familial Hypercholesterolemia
Diuretic therapy at the heart-kidney interface: from acute decongestion to long-term de-escalation in heart failure with reduced ejection fraction
Mimics and Chameleons: A Patient with Accidental Hypothermia and Myocardial Infarction
Investigating the TASK1 potassium channel in equine atrial myocardium as a potential treatment target for atrial fibrillation
Heart failure management and outcomes: what can we learn from Japan?
Predicting diuretic response in acute heart failure: accurate forecasts, but better decisions?
Right Ventricular Hydatid Cyst: A Rare Cause of Right Heart Failure in Pregnancy
Shared Genetic Architecture Between Mental Disorders and Heart Failure Subtypes: A Comprehensive Multitrait Genome-Wide Analysis
Sex Differences in the Associations of Age-Related Genetic Predisposition With Incident Atrial Fibrillation: A Prospective Cohort Study
Efficacy and Safety of Pharmacologic Therapies in Nonobstructive Hypertrophic Cardiomyopathy: A Systematic Review
Greater Neighborhood Resources Predict Reduced In-Hospital Death for Children With Heart Failure and Cardiomyopathy
Combined Prognostic Value of Cardiac Magnetic Resonance-Derived Myocardial Extracellular Volume and the Fibrosis-4 Index in Patients With Heart Failure With Preserved Ejection Fraction
Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review)
MAPK15 induces cardiomyocyte senescence and atrial fibrillation by promoting mitochondrial calcium overload via palmitoylating Mcub at the C91 residue
Diagnostic accuracy of artificial intelligence (AI)-based models for acute myocardial infarction: a systematic review and meta-analysis
Safety, Efficacy and Cost of Same-Day Discharge after Pulsed Field Ablation for Atrial Fibrillation: A Sub-study of the Multicentre SENTINEL Registry
The Association Between Myocardial Infarction and Loneliness Among Adults in the Saudi Population: A Comparative Analytical Study
Mindfulness-based perioperative care, sleep architecture, autonomic regulation, and early atrial tachyarrhythmia recurrence after radiofrequency catheter ablation for atrial fibrillation: a prospective observational cohort study
Powerful cholesterol drug cuts heart attack risk by 31%
ONCOLOGY
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FOXC1–GMDS axis-driven glycolytic reprogramming promotes tumor progression in triple-negative breast cancer
TACE and yttrium 90 based combination therapies are associated with distinct post-treatment tumor microenvironment profiles in unresectable hepatocellular carcinoma
High prevalence of TROP2 expression identifies EBV-positive gastric cancer as a candidate for TROP2-directed antibody-drug conjugates
Efficacy of an AIMP1-Derived Peptide (NeoPep-S) for Radiation-Induced Dermatitis in Breast Cancer Patients: A Prospective Randomized Active-Controlled Trial
Re: "Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer."
ENZARAD (ANZUP 1303): Phase 3 Trial of Enzalutamide With Androgen Deprivation Therapy and Radiation Therapy in High-Risk Localized or Locally Advanced Prostate Cancer
COMPANION-002: A Randomized Phase 2/3 Trial of Tovecimig Plus Paclitaxel versus Paclitaxel Alone as a Second-line Therapy in Patients with Advanced Biliary Tract Cancer
STAT+: Most cancer drugs approved by European regulators lack a high clinical benefit, analysis finds
STAT+: Pharmalittle: We're reading about a cancer vaccine, an experimental pancreatic cancer drug, and more
Dual-targeted therapy shows promise against metastatic triple-negative breast cancer
Scientists discover a hidden immune weapon against deadly lung cancer
LM103, an autologous tumor-infiltrating lymphocyte monotherapy, in patients with advanced melanoma resistant to standard therapy
p300 activity and subcellular localization associate with tumor aggressiveness and clinical outcome in triple-negative breast cancer
Jemperli Could Let Some Rectal Cancer Patients Skip Chemotherapy, Radiation And Surgery
Why painful arthritis can return stronger after cancer treatment
The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial
Scientists just found a way to fight lung cancer and muscle wasting at the same time
Vitamin D drug may help crack pancreatic cancer’s protective shield
Scientists say house cats could help unlock better cancer treatments for humans
A major risk of breast cancer screening may have been overestimated for decades
NEUROSCIENCE
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Constructing functional neural circuits to model amyotrophic lateral sclerosis with induced pluripotent stem cell-derived brain organoids
Comprehension of ambiguous sentences in Alzheimer's disease: A study with Brazilian older adults
Machine Learning Approach Investigating Differentially Expressed Genes Associated With Parkinson's Disease on Exposure to Pesticides Through Nutritional Uptake
Gut Microbiota in Alzheimer's Disease and Healthy Aging: Mechanisms, Prevention Strategies and Healthcare Burden
Unlocking therapeutic potential of Wnt signaling pathway in neurodegenerative diseases
Twenty-five years of progress in Parkinson's disease research: from dopamine replacement to biological definition and regenerative therapy
The Multi-Faceted Nature of Limb Apraxia in Neurodegenerative Diseases: a Systematic Review
Neurotrophic regulation of lipid metabolism in Alzheimer's disease: Mechanisms and therapeutic implications
Sex differences in exercise-induced pro-inflammatory cytokine responses relevant to Alzheimer's disease: A systematic review and meta-analysis
Diabetes mellitus accelerates preclinical Alzheimer's disease progression by amplifying the amyloid-to-tau pathway and attenuating brain-cognition resilience
Spatially Resolved Multiplex Detection of Cytokines in Parkinson's Disease Rat Brain via CRISPR/Cas Biosensing
Temporomandibular Joint Disorder in Parkinson's Disease Patients
Ambulatory Episodic Hypertension in Parkinson's Disease With Orthostatic Hypotension
Telling the Future: Narrative Frameworks to Navigate Ethical Challenges in Prodromal Parkinson's Disease
Rising from the Floor: A Movement Analysis of Older Adults and Individuals With Parkinson's Disease
Cell Painting method reveals drug differences in 3D cancer cells
"Mind-blowing" Alzheimer’s breakthrough: Two hours of sleep restored without clearing brain plaques
Scientists may have overlooked a hidden Alzheimer's culprit for decades
The hidden math of Alzheimer's could point to new treatments
Genentech pays Alector $100M for preclinical Parkinson’s prospect
INFECTIOUS DISEASE
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An α1D-adrenergic receptor vaccine protects against HFpEF in mice
Linear cap-independent mRNA vaccines as an emerging vaccine platform
Moderna mRNA vaccine almost halves the risk of skin cancer returning
Manganese-Coordinated Rhein Hydrogel as a Vaccine Adjuvant for Synergistically Enhanced Humoral and Cellular Immunity
A global genomic analysis of Streptococcus equi subsp. zooepidemicus reveals clade-specific pathogenic and antimicrobial resistance profiles with several mobile genetic elements as key adaptive drivers
mGem: Antibiotic tolerance across the growth-rate continuum in chronic human infections
Antibiotic Resistance in India Over a Decade: A Systematic Review and Meta-analysis of Clinical and Molecular Evidence (2015-2025)
Molecular Characterization and Antimicrobial Resistance Patterns of Multidrug-resistant Gram-negative Bacilli Isolated from Intensive Care Unit Patients in a Tertiary Care Hospital
Association Between Sputum Consistency and Extubation in Mechanically Ventilated Patients with Severe Pneumonia Receiving Nebulized Antibiotic Therapy
Retail Frozen Blended Beverages as Vehicles for Opportunistic Antibiotic-Resistant and Biofilm-Forming Bacteria
Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial
Moderna mRNA vaccine almost halves the risk of skin cancer returning
Patient acceptance of preventive antibiotic treatment for tuberculosis: a qualitative study in London, UK
Osivax reports phase 2b data for OVX836
High-risk antimicrobial resistance genomic traits in multidrug-resistant Salmonella across China’s food chain: projections to 2050
Safety and immunogenicity of a BPL-inactivated, whole-virus, universal influenza vaccine: a randomized, double-blinded, double-dummy, placebo-controlled, phase 1 clinical trial
Bioengineering strategies for improving the immunogenicity of mRNA vaccines
160-million-year-old proteins show surprising power against superbugs
AI-guided optimization for thermostable mRNA vaccines
Recoding by N1-methylpseudouridine guides rational mRNA vaccine design
LIQUID BIOPSY
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A DNA Logic-Gated Cascade Amplification Biosensor for Highly Specific Electrochemical Detection of Circulating Tumor Cells
Prognostic value of circulating tumor cells in stage III and IV melanoma: a systematic review and meta-analysis
Chemiluminescence and electrochemiluminescence biosensors for cancer biomarker detection: analytical advances, liquid-biopsy applications, and translational challenges
Cerebrospinal fluid cell-free DNA methylation captures disease-specific biology in tauopathies
Acoustofluidic enrichment of small extracellular vesicles: physical principles, microfluidic implementations, and prospects for Parkinson's disease liquid biopsy
Circulating tumor DNA in gynecologic oncology: moving from the present into the future
Inferring tissue origin from cell-free DNA in metastatic cancer
Attitudes of cancer patients toward ctDNA-based liquid biopsy for follow-up
Diagnostic Performance of cfDNA-Based Liquid Biopsy for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Integrated microfluidic platform for the capture and identification of circulating tumor cells using dielectrophoresis and image recognition
Extended Non-Invasive Prenatal Testing for Chromosomal and Monogenic Disorders by Cell-Free DNA Sequencing: A Blinded Comparison With Amniocentesis
The prospects and challenges of the use of cell-free DNA as a diagnostic and prognostic biomarker for oral cancer in Sub-Saharan Africa
Paxalisib with Trastuzumab for HER2-Positive Metastatic Breast Cancer with Active Brain Metastases: A Phase II Trial with Integrated Plasma and CSF ctDNA Analyses
A nine-year CLIPPERS-like syndrome at the boundary of CNS T-cell lymphoproliferation: clinicopathological and CSF cell free DNA findings
tsRNAs in HCC: Biology, liquid biopsy and therapy
Multi-omics liquid biopsy for leptomeningeal metastases in lung cancer: from molecular mechanisms to precision diagnosis and treatment
Prognostic value of circulating tumor DNA in esophageal and gastric cancer by treatment stage: A systematic review and meta-analysis
Profiling circulating tumor DNA for recurrence prediction and prevention in hepatocellular carcinoma following liver transplantation
Value and research advances of ctDNA in perioperative therapy for non-small cell lung cancer
Circulating citrullinated proteins as candidate liquid biopsy analytes in cancer